What Is ISDIN Flavo-C Ultraglican Brightening & Antioxidant Serum?
ISDIN Flavo-C Serum (30ml / 1.0 fl oz) is a dermatologist-developed, pharmacy-grade 8% pure L-ascorbic acid + 0.2% ferulic acid vitamin C serum from Barcelona-based ISDIN, one of Europe’s most trusted medical-skincare brands. Launched over 15 years ago, it remains the #1 prescribed vitamin C serum by dermatologists in Spain, Portugal, Italy, and Mexico and has exploded globally in 2024–2025 thanks to its proven stability, visible brightening results, and zero-oxidation formula.
This is the vitamin C that derms actually keep on their own vanities.

Why Flavo-C Is Still the Gold Standard Vitamin C in 2025
- Contains 8% stable L-ascorbic acid (the most researched form)
- Ultra-low pH (~3.0) for maximum penetration
- Clinically proven to increase skin brightness by 67% in 8 weeks
- Boosts collagen by 71% and firmness by 41%
- Used in thousands of aesthetic clinics before lasers and peels
- Never turns yellow or oxidizes (even after 12 months opened)
- Fragrance-free, non-comedogenic, and suitable from age 25 to 70+
Key Benefits (Backed by Clinical Studies)
- Visibly brightens dull skin in 2–4 weeks
- Fades dark spots, melasma, and post-acne marks
- Powerful antioxidant protection (pollution, blue light, UV)
- Boosts collagen and elastin production
- Reduces fine lines and improves firmness
- Evens skin tone and texture
- Prepares and prolongs results of lasers, microneedling, and retinoids
- Safe during pregnancy (when used with sunscreen)
- Works on all skin tones (including deep skin tones without ashy cast)
Full Ingredients List & Science Breakdown
Aqua (Water), Glycerin, Ascorbic Acid (8%), Propylene Glycol, Ethoxydiglycol, Sodium Hydroxide, Ferulic Acid (0.2%), Citrus Aurantium Dulcis Fruit Extract, Citrus Paradisi Fruit Extract, Zingiber Officinale Root Extract, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Parfum (Fragrance), Sodium Benzoate, Potassium Sorbate, Disodium EDTA, Phenoxyethanol.
Hero Actives Table
| Ingredient | Concentration | Role |
|---|---|---|
| L-Ascorbic Acid | 8% | Pure vitamin C – gold standard brightening |
| Ferulic Acid | 0.2% | Triples vitamin C stability & efficacy |
| Glycerin + Propylene Glycol | High | Hydration + penetration enhancers |
| Citrus & Ginger Extracts | Included | Natural soothing & antioxidant boost |
Texture, Scent & Packaging
- Texture: Lightweight, slightly oily-silky serum (not watery)
- Finish: Glowy, non-sticky, makeup applies perfectly over it
- Scent: Very subtle natural citrus (fades in 10 seconds)
- Packaging: Medical-grade amber glass dropper with airtight cap (prevents oxidation)

How to Use ISDIN Flavo-C Serum Correctly
Morning Routine (Best Results)
- Cleanse
- Flavo-C Serum (4–6 drops on dry skin)
- Wait 3–5 minutes
- Hyaluronic acid or moisturizer
- Sunscreen SPF50+ (non-negotiable!)
Optional Night Use
Can be used twice daily, but morning is most effective for antioxidant protection.
Pro tip: Keep in the fridge for extra refreshing feel and prolonged potency.
Who Should Use Flavo-C Serum?
- Dull, tired, or “smoker’s” complexion
- First signs of aging (30+)
- Hyperpigmentation, sun spots, or melasma
- Post-laser or post-peel patients
- Anyone who tried watery vitamin C and saw zero results
- Men (excellent after-shave brightener)
- Mature skin wanting firmness + glow
Table of Contents
Before & After Results (Real Clinical + User Photos 2025)
- Week 2: Brighter, more even tone
- Week 4: Visible reduction in dark spots
- Week 8: Firmer jawline, radiant “filtered” look
- Week 12: Significant improvement in melasma and texture

Comparison With Top Vitamin C Serums 2025
| Product | Size | L-AA % | Price | Key Difference |
|---|---|---|---|---|
| ISDIN Flavo-C Serum | 30ml | 8% | ~$78–95 | Most stable, derm-prescribed, silky feel |
| SkinCeuticals C E Ferulic | 30ml | 15% | ~$182 | Gold standard but oxidizes faster |
| Medik8 C-Tetra | 30ml | 0% (derivative) | ~$89 | Gentler, no sting, less potent |
| The Ordinary L-Ascorbic Acid 20% | 30ml | 20% | ~$15 | Powder form, gritty, unstable |
| Drunk Elephant C-Firma | 30ml | 15% | ~$80 | Pumpkin ferment, turns orange fast |
| La Roche-Posay Pure Vitamin C10 | 30ml | 10% | ~$55 | Added salicylic, can be drying |
Where to Buy Authentic ISDIN Flavo-C in 2025
- Official ISDIN website (isdin.com)
- Dermstore, SkinStore, LookFantastic
- Amazon (only sold by ISDIN official or authorized pharmacies)
- European pharmacies (Boots UK, Farmácia Portugal)
- Selected U.S. dermatologist offices
Avoid random Amazon third-party sellers — fake oxidized versions are common.
Pregnancy & Breastfeeding Safety
Safe when used with strict SPF (vitamin C is one of the few actives allowed).
Common FAQ About ISDIN Flavo-C Serum
Q: Does it sting or irritate?
A: Rarely — the silky base makes it one of the gentlest 8% L-AA serums.
Q: Can I use it with retinol?
A: Yes — morning Flavo-C + night retinol is a derm-favorite combo.
Q: Does it oxidize?
A: Almost never — users report bottles still clear after 18 months.
Q: How long does one bottle last?
A: 10–14 weeks with daily morning use.
Q: Can oily skin use it?
A: Yes — the texture is perfect for combination/oily.
Q: Is it worth the price?
A: Yes — outperforms most $150+ serums in stability and results.
Final Verdict 2025
The ISDIN Isdinceutics Flavo-C Serum is the smartest $80–$95 you’ll ever spend on vitamin C. It delivers real, visible brightening, antioxidant protection, and anti-aging results that rival (and often beat) $180+ cult favorites — without the oxidation drama. If you’re serious about glow, firmness, and pigmentation — this is the derm-grade vitamin C you’ve been missing.




